Research Library

This scientific research is for informational use only. The results reported may not necessarily occur in all individuals. Care/of provides this information as a service. This information should not be read to recommend or endorse any specific products.


In recent years, Elderberry has been the subject of both in-vitro and in-vivo research. In these studies, Elderberry has demonstrated multiple immunomodulatory properties suggesting broad immune support.

In 2016, a randomized, double-blind placebo-controlled clinical trial was conducted to assess the effects of elderberry extract on physical health during long-haul airplane flights. Researchers evaluated 312 healthy passengers flying overseas from Australia on a minimum 7-hour flight. The passengers were split into two groups, one receiving placebo, and another receiving 900mg per day of elderberry extract. The participants were surveyed at baseline, just before travel, and again 4 days after travel. Comparing the two groups, there were more symptoms in the placebo group; however, it was not significant (17 in the placebo group, 12 in the elderberry group.) Furthermore, healthy passengers that took elderberry showed fewer common air travel respiratory occurrences during travel on long-haul flights than placebo. (2).

Antioxidant properties

The two most common types of Elderberry are the European Elderberry (Sambucus nigra) and the American Elderberry (Sambucus canadensis). Our Elderberry is a Haschberg variety of the European Elderberry that is native to countries like Poland, Hungry, Ukraine and Austria. This variety of Elderberry has been tested and shown in clinical studies to contain some of the highest naturally occurring levels of anthocyanins and polyphenols when compared to other Elderberry varieties. Anthocyanins are naturally occurring pigments belonging to the group of flavonoids, a subclass of the polyphenol family. Anthocyanins are naturally occurring pigments that give certain fruits their alluring dark color, while polyphenols are naturally occurring micronutrients with antioxidant properties. These compounds have been scientifically shown to help support a healthy strengthening of the immune system.

Elderberry is only harvested once a year. Factors outside of human control, like inclement weather or a poor harvest, can negatively impact supply. Our material undergoes extensive testing to ensure its authenticity and purity.

Elderberry juice powders are typically spray dried on a carrier like maltodextrin using a hot spray dried process that can remove some of the key antioxidants. The juicing process may also remove the naturally occurring fiber found naturally occuring in the Elderberry fruit. A special patented infrared, low temperature drying technology is used for our Elderberry juice concentrate which helps to maintain the naturally occurring phenolic levels of polyphenols and anthocyanins throughout the manufacturing process. A partially hydrolyzed guar gum fiber has been added to our Elderberry to help support nutrient absorption in the human body and maintain the naturally occurring levels of the antioxidants throughout processing. Our juice concentrate is also solvent-free, which also helps to maintain the integrity of the elderberry compounds, and is derived from the fruit of the Elderberry, a particularly enriched antioxidant part of the plant.